Following, available to 160 mg in combination with Provas applications, there are more detailed information:
- High blood pressure
- Heart muscle weakness
In the following variants, Provas 160 mg is available:
|Pack size and dosage form||Potency dosage per film-coated tablet)||Cheapest price per Pack|
|98 Film-coated tablets||160 Mg of valsartan||Price 97,07 EUR (10,00 EUR), (0,00 EUR shipping) price comparison|
|56 Film-coated tablets||160 Mg of valsartan||66,92 EUR|
|28 Film-coated tablets||160 Mg of valsartan||Price 36,59 EUR (5.00 EUR), (3,95 EUR shipping) price comparison|
The following substance not effective components are part of the drug:
- Eisen(II,III)-OXID (E 172)
- Eisen(III)-OXID (E 172)
- high colloidal silicon dioxide
- Magnesium stearate
- Iron oxide hydrate (E 172)
- MACROGOL 8000
- Microcrystalline cellulose
- Titanium dioxide
So Provas has 160 mg
Provas 160 mg contains the active ingredient valsartan. Learn more on the applications and the action of valsartan below. Read also the information about the active group of angiotensin II receptor antagonists, among which the active ingredient valsartan.
Fields of application of the active substance: valsartan
Valsartan is used for the treatment of non-organ-related high blood pressure (so called essential or primary hypertension).
Are not tolerated by the patient ACE inhibitors, valsartan can be given also to the therapy in heart muscle weakness.
Following applications of valsartan, in-depth information is available:
- High blood pressure
- Heart muscle weakness
Effect of valsartan
Valsartan belongs to the drug group of angiotensin II receptor antagonists. The drug blocks the binding site for the blood pressure-boosting hormone Angiotensin II in vascular muscle cells. This angiotensin can dock no longer II, absence of a contraction of blood vessels and increasing blood pressure.
The hypotensive effect two hours after taking committed in most patients. The maximal blood pressure reduction occurs four to six hours and lasts over 24 hours. In the longer term treatment, the optimal blood pressure reduction is generally two to four weeks after the start of treatment achieved and maintained a long term therapy.
Valsartan is degraded by the liver and kidneys and excreted. Therefore the doctor should customize the dose in patients with hepatic and/or renal deficiency.
Warnings & precautions
So far the drug may affect the responsiveness that driving and using machines are dangerous.
A salt and/or fluid deficiency by the doctor should be offset prior to therapy with the drug.
Appropriate measures of contraception must be taken during treatment with the drug.
Prior to the application of the drug in women of childbearing age, a pregnancy is to exclude.
Medical care be taken when treating patients with liver dysfunction.
Medical care be taken when treating patients with renal impairment.
Medical care be taken when treating patients with heart disease.
Medicines can cause allergic reactions. Evidence for this can be: redness, runny nose, itching, swelling of the mucous membrane, itching and redness of the eyes, narrowing of the Airways (asthma). In rare cases, there may be allergic shock with loss of consciousness.
What interactions of active substance of valsartan in Provas 160 mg are known? It is important to note that the interactions can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).
The effect of valsartan can be increased with concurrent administration of other hypotensive means. Regular blood pressure checks are therefore required.
Simultaneous administration of potassium-drainage materials, potassium supplements or other potassium concentration should enhancing resources (such as the Blutgerinnungs inhibitory Antikoagulazien and heparin) very carefully and take place only during regular inspection of potassium by the attending physician.
An increase in the blood lithium concentration and toxicity of lithium (drugs) has been reported with concurrent administration of ACE inhibitors. No therapy experience with regard to the simultaneous use of valsartan and lithium are available however. Nevertheless, a medical surveillance of blood lithium concentration is recommended.
Should treatment with low doses (a film-coated tablet of Provas 80 milligrams once a day) are started. A maximum blutdrucksenkender effect is achieved after four weeks. With insufficient blood pressure reduction the dose on a film-coated tablet of Provas can be increased 160 milligrams once a day.
The medication must be deposed not abruptly, but should be reduced after consultation with the doctor gradually.
The following information 160 mg in General, pregnancy & lactation, and children about contra-indications for the purposes of Provas. It is important to note that the contra-indications can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).
When Provas cannot use 160 mg?
When hypersensitivity to valsartan, the active substance should not be given.
In patients with severe liver dysfunction, the bile ducts of in cirrhosis (biliary cirrhosis), biliary tract closure, severe renal impairment (Kreatininclearance under ten milliliters per minute) as well as patients obligatory in dialysis the use of valsartan is also forbidden.
Relative contraindications for the use of valsartan are bilateral renal artery reduction (renal artery stenosis) or unilateral reduction of renal artery with single kidney, as well as the State after Renal Transplantation. The same is true in patients with reduction of heart valve (aortic or mitral valve stenosis) or an abnormal thickening of the heart muscle (hypertrophic cardiomyopathy). In these cases, the doctor will decide individually on a therapy. Regular medical monitoring is urgently needed.
The primary Aldosteronism (disturbed hormone excreted of kidney) is not recommended for the application in General. This disorder refers to not on Angiotensin II receptor antagonists.
What must you consider when pregnancy and breast-feeding?
Valsartan may be applied during pregnancy and lactation.
Angiotensin II receptor antagonists, including valsartan can interfere with circulation thereof and to their development as well as ACE inhibitors in pregnancy after the formation of the child’s organs. The application in the second and third pregnancy can therefore renal impairment, a reduction of Fruchwassermenge and slowdown in the growth of the skull bone and cause neonatal kidney failure, low blood pressure, and excess of potassium in the blood. The use of ACE inhibitors and Angiotensin II receptor antagonists in the first third of the pregnancy is not recommended due to lack of data from studies and is expressly prohibited in the time thereafter.
Determined during treatment with the drug a pregnancy or a pregnancy is planned, valsartan must be set down as quickly as possible by the attending physician. This will also decide an alternative therapy.
Because it is not known whether the active ingredient in mother’s milk is over, mothers may not breastfeed during treatment. Before the start of treatment must be breastfed off therefore.
What is taken into account in children?
Children and young people should receive no valsartan. No experience with the treatment are available in this age group.
What side effects can the active ingredient valsartan in Provas 160 mg have? Below, learn the most important thing to possible, well-known side effects of valsartan in Provas 160 mg. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the drug form of the drug (for example, Tablet, syringe, ointment).
Common side effects: drowsiness, dizziness at layer change, headache, infections of the upper respiratory tract, viral infections, drop in blood pressure when sitting or standing up.
Uncommon side effects: boost the liver function tests, fatigue, Hautauschlag, heat, back pain, nausea, cough, flu-like symptoms, abdominal pain, diarrhea, throat mucous membrane inflammation, swelling of the skin, tissue water collections, vomiting, airway inflammation (bronchitis), cold, depression, insomnia, loss of consciousness without apparent cause, heart failure, arthritis, conjunctivitis, Epistaxis.
Rare side effects: joint pain, muscle pain, swelling of the vessel, swelling of skin and mucous membrane, skin rash, hives, itching, waste of individual or all groups of white blood cells, nerve pain.
Very rare side effects and individual cases: inflammatory skin disease with grouped occurring bubbles, bleeding, acute renal failure, renal impairment, weakness of the kidney.
Specialties: Occasionally observed during treatment with valsartan a drop of Red pigments and the Hämatokrits (mass for the toughness of the blood). Still was also reported an increase of liver function values in patients with high blood pressure. Therefore, regular medical checks of all the important blood parameters are necessary.