Loperhoe

Application area called by the manufacturer

To this, related with Loperhoe application area there is in-depth information:

  • Diarrhea

Variant comparison

Loperhoe is available in the following variants:

Pack size and dosage form Potency (dose per Tablet) Cheapest price per Pack
10 Tablets 2 Mg loperamide Price 10,95 EUR (5.00 EUR), (3,95 EUR shipping) price comparison
50 Tablets 2 Mg loperamide 14,53 EUR (5.00 EUR), price (3,95 EUR shipping) price comparison
20 Tablets 2 Mg loperamide 12.47 EUR (5.00 EUR), price (3,95 EUR shipping) price comparison

Other components

The following substance not effective components are part of the drug:

  • high colloidal silicon dioxide
  • Magnesium stearate
  • microcrystalline cellulose

How Loperhoe works

Loperhoe contains the active ingredient loperamide. Learn more about the applications and the action of loperamide below. Read also the information to the API group against diarrhoeal diseases, among which the active ingredient loperamide. Please note the special effect of Loperhoe is also

Application of the active substance: loperamide

The active ingredient is used for the symptomatic treatment of acute and chronic diarrhoea (Diarrhöen). It comes in diarrhoeal diseases used caused is not to identify or not causally can be handled for other reasons.

In the long term, loperamide may be applied only under medical observation.

Following applications of loperamide, in-depth information is available:

  • Diarrhea

Mode of action of loperamide

Loperamide belongs to the Group of funds against diarrhoeal diseases. The active ingredient is a so-called Durchfallstopper. That is, he combated not the cause of Durchfalls, but inhibits the Darmbewegung. This accesses the active ingredient at the same binding sites (receptors) on sweeping, entailing the clogging effect of opioid pain relievers. The occupation of these so-called my opiate receptors inhibits the intestinal movements, verlägert the residence time of Darminhaltes and allows for a greater recovery of water and minerals. This thickens the tract that the diarrhea comes to a standstill.

The intestinal flora (settlement with beneficial bacteria) is not altered by loperamide. The increase of stress in the anal muscles, which are the symptoms of Stuhldrang and incontinence repair is favorable in the treatment of Durchfalls with loperamide.

Special features of the effects of Loperhoe

The active ingredient is present in this drug not in pure form, so there may be slight deviations from the active ingredient quantity specified here.

Application area according to manufacturer’s specifications

  • Treatment of acute and chronic diarrhea, where no treatment of the cause is possible

Warnings & precautions

The drug can trigger an allergic reaction.

In the long term, the drug only under medical observation may be applied.

Most important measure when diarrhea is the replacement of fluids and minerals in prophylaxis.

In AIDS patients the treatment must be canceled after such an abdomen driven on after taking the drug immediately.

If no significant improvement has occurred in acute diarrhea 48 hours after the start of therapy, the medication should be discontinued.

Especially for children and elderly people is to ensure adequate fluid and electrolyte replacement.

The medicinal product should be applied not more than four weeks without medical supervision.

The product is not suitable for children under eight years of age.

Medicines can cause allergic reactions. Evidence for this can be: redness, runny nose, itching, swelling of the mucous membrane, itching and redness of the eyes, narrowing of the Airways (asthma). In rare cases, there may be allergic shock with loss of consciousness.

Interactions

Which of the active substance loperamide in Loperhoe interactions are known? It is important to note that the interactions can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

The simultaneous use of quinidine (against cardiac arrhythmias) or ritonavir (against AIDS) leads to a two-to threefold increase in the loperamide concentration in the blood. It is assumed that this frequency of the adverse effects of loperamide increases.

Dosage

Adults begin the treatment in acute diarrhea with two tablets (four milligrams loperamide). Then, they occupy a Tablet after each unformed stool. A daily dose of 8 tablets (16 milligrams of active ingredient) should not be exceeded. For chronic diarrhea, the daily dose is two tablets.

Children who are older than eight years, occupy a tablet on acute diarrhea at the start and after each unformed stool. The daily maximum dose is four tablets. For chronic diarrhea, the daily dose is one tablet.

The tablets are taken whole with sufficient fluid.

The medicinal product should be applied not more than two days without medical advice in acute diarrhea.

Especially for children and elderly people is to ensure adequate fluid and electrolyte replacement.

Contra-indications

The following information about contra-indications in the application of Loperhoe in General, pregnancy & lactation, and in children. It is important to note that the contra-indications can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

When may Loperhoe not be used?

The active ingredient may not be applied if a hypersensitivity to loperamide is known. Also the active ingredient may be not taken in diseases and complaints, which must prevent a slowdown of intestinal activity such as bloating, constipation, Darmlähmungen, or intestinal obstruction.

When diarrhoea with fever or bloody stool and diarrhea caused by the ingestion of antibiotics (pseudomembranous colitis), loperamide may be not prescribed also. This also applies to gastro intestinal inflammation (ulcerative colitis) in the acute thrust, as well as for bowel disease caused by bacteria such as salmonella, Shigella and Campylobacter.

Only after careful risk benefit by the physician, patients should be treated with chronic diarrhea and patients with existing or made by liver disease with loperamide.

What must you consider when pregnancy and breast-feeding?

Sufficient experience are not available. That is why the active ingredient in pregnancy and breastfeeding should not apply. The active ingredient is transferred into breast milk.

What is taken into account in children?

Children under two years of age may not be treated with the active substance.

Children aged between two and twelve years should be treated only after careful risk benefit by the doctor with loperamide.

Due to the high content of active substances, capsules and tablets for children aged between two and eight years are not suitable, for this age group, the doctor must calculate the dosage according to body weight.

Side effects

What side effects can the active ingredient loperamide in Loperhoe have? Below, you will learn the most important thing possible, well-known side effects of loperamide in Loperhoe. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the drug form of the drug (for example, Tablet, syringe, ointment).

Common side effects: dry mouth, nausea and vomiting, flatulence, air and gas accumulation in the gut, stomach cramps and colic, constipation, headache, dizziness.

Rare side effects: skin rashes and itching, Darmlähmung or intestinal obstruction (ileus), stimulating gastric or colonic extensions with severe disorders of transport of constricting (megacolon), sleepiness, urinary.

Very rare side effects: allergic reactions to anaphylactic shock, angioedema (swelling and redness of the skin), painful blistering of the skin and mucous membranes (Stevens-Johnson Syndrome), severe inflammatory skin redness (erythema multiforme), syndrome of verbrühten skin (Lyell’s syndrome).

Specialties: AIDS patients who get a body driven up after administration of loperamide, need to immediately stop the diarrhea treatment.

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