Application area called by the manufacturer

To this, with Marvelon related application area there is in-depth information:

  • Contraception

Other components

The following substance not effective components are part of the drug:

  • Lactose 1H2O
  • á tocopherol
  • hochdisp. Silicon dioxide
  • Hypromellose
  • Potato starch
  • MACROGOL 400
  • Povidone
  • Stearic acid
  • Talcum powder
  • Titanium dioxide (E 171)

Marvelon appears

Marvelon contains the active substance combination ethinyl estradiol + Desogestrel. Learn more about the applications and the action of ethinyl estradiol + Desogestrel below. Read also the information about the active group of estrogen-progestin combinations to prevent, to which the active substance combination ethinyl estradiol + Desogestrel belongs.

Fields of application of the combination of active ingredients: ethinyl estradiol + Desogestrel

The combination of active ingredients of ethinyl estradiol and Desogestrel is used to the hormonal contraception (“pill”, “Birth control pill”). In addition, the active ingredients can be used also to normalize cycle disorders. These include too rare or too frequent bleeding (dysmenorrhea).

Following applications of ethinyl estradiol + Desogestrel in-depth information are available:

  • Contraception
  • Cycle disturbances and complaints
  • Effect of ethinyl estradiol + Desogestrel
  • Ethinyl estradiol and Desogestrel belong to the Group of estrogen progestin combinations to prevent.

Ethinyl estradiol is related to the body’s own hormone estradiol from the Group of estrogens. Desogestrel is a progestin (Gelbkörperhormon) and is similar to progesterone.

The combination of estrogen and progestin supported the preparation of the body on a pregnancy, ovulation and the period of regression in the menstrual cycle of a woman. This is done by these hormones are awarded varies on certain days of the cycle.

By using the combination of the active ingredients, increased amounts of oestrogen and progestin are offered the body. So a pregnancy is faked the body. As a result, ovulation is inhibited and the thickening of the uterine lining, which is necessary for an implantation of the egg, absence. This means a double protection against pregnancy. Desogestrel in addition thickened the mucus at the entrance of the uterus so that sperm can get worse. Through its positive influence on the development of the endometrium, Desogestrel can counteract cycle disorders based on irregular or irregular bleeding (so the removal of the uterine lining).

Warnings & precautions

Diarrhea and vomiting can reduce the efficacy of the combination.

A multiple sclerosis can be strengthened by combining.

Does the combination not protect against HIV infection or other sexually transmitted diseases.

Spotting can be indications of an attenuated efficacy of the combination.

Risk differences for a venous thromboembolism between the different combined oral contraceptives.

Medicines can cause allergic reactions. Evidence for this can be: redness, runny nose, itching, swelling of the mucous membrane, itching and redness of the eyes, narrowing of the Airways (asthma). In rare cases, there may be allergic shock with loss of consciousness.

Should you perceive signs of an allergic reaction, immediately inform a doctor.


What interactions of the active substance combination ethinyl estradiol + Desogestrel in Marvelon are known? It is important to note that the interactions can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

The contraceptive action of the combination of ethinyl estradiol and Desogestrel can humiliated by common application of certain active substances or lifted. These include

  • Sleep aid from the Group of barbiturates
  • the antibiotic rifampicin, griseofulvin, ampicillin and tetracycline
  • St. John’s wort
  • Antiepileptics like Barbexaclone, Hydantoin, carbamazepine, phenytoin, Primidone, Oxcarbazepine, topiramate and Felbamate
  • the Gichtmittel Phenylbutazone
  • Activated carbon

Because the combination affects blood sugar, insulin and oral antidiabetic drugs may in their dose must be adjusted. The effect of theophylline may be extended by common application with ethinyl estradiol and Desogestrel. Treatment with ethinyl estradiol can lead to an increased blood levels of thyroid hormones. This must be reflected in investigations of the thyroid gland.


Taking starts taking a film-coated tablet on the first day of the cycle (the first day of menstruation). The 21 tablets from a pack should be taken every day in a row, as possible in the evening at the same time. This is followed by a seven-day break from the revenue. During this time, it comes to menstruation. Four weeks after the beginning of the revenue to continue taking begins with a new pack of Marvelon the same day of the week.

A forgotten Tablet revenue must be rescheduled at the latest within a period of 12 hours. A later taking the contraceptive action in this cycle is no longer reliable. In such a case is to skip the forgotten tablet, but as usual to use up the Pack, to avoid a premature bleeding. In addition, mechanical contraceptives (condom) should be applied.


The following information about contra-indications for the purposes of Marvelon in General, pregnancy & lactation, and in children. It is important to note that the contra-indications can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

When Marvelon cannot use?

The ingestion of ethinyl estradiol and Desogestrel must be stopped immediately if:

  • Hypersensitivity against one of the active ingredients of the combination
  • Pregnancy and breast-feeding
  • existing or former malignant tumors that would grow further by administration of estrogens (such as breast cancer)
  • Herpes infections in a previous pregnancy (herpes gestationis)
  • untreated growths of the uterine lining (endometriosis)
  • diagnostic in clarified bleeding from the vagina
  • acute or previous severe liver disorders (such as liver tumors, liver, jaundice or Porphyria), at least as long as that certain liver (transaminases) not have normalized

Sickle cell anemia

acute or previous blood vessel diseases which have resulted in occlusions (thrombosis) of arteries or veins such as serious diseases, vein thrombosis, phlebitis (thrombophlebitis), pulmonary embolism, stroke, angina pectoris, heart attack, and valvular heart disease

  • hard behandelbarem high blood pressure, which increases the risk of more occlusions
  • severe lipid metabolism disorders or obesity
  • Middle ear hearing loss who has made worse during previous pregnancies.

The following diseases the combination of active substances can be applied while, the doctor must however, check that the development of the treatment through ongoing control of the corresponding laboratory values and, if necessary, cancel the treatment:

  • Breast cancer in the family (related first degree)
  • Poor circulation to the arms, hands and legs
  • Rise in blood pressure
  • Cardiovascular and renal impairment
  • previous lighter liver and gallbladder diseases
  • Migraine or severe headache
  • Depression
  • Diabetes (diabetes mellitus)
  • Epilepsy
  • Asthma
  • Chorea minor (Chorea)
  • multiple sclerosis
  • treated growths of the uterine lining
  • lighter lipid metabolism disorders or significant overweight
  • Diseases of breast (Mastopathy)
  • benign uterine tumors
  • pronounced tendency toward varicose veins

The application of ethinyl estradiol and Desogestrel favours the emergence of occlusions (thrombosis), which can lead to life-threatening cardiovascular disease. This danger can be through additional risk factors as smoking, high blood pressure, blood clotting or of lipid metabolism disorders, as well as longer restraining further be increased (for example through confinement).

What must you consider when pregnancy and breast-feeding?

The scope of ethinyl estradiol and Desogestrel excludes a treatment with the combination of the drug during pregnancy.

The production of breast milk can be reduced by ethinyl estradiol and Desogestrel. Also, small amounts of active ingredient in breast milk and hence in the infant can go over. To avoid damage to the child before an application of the combination of active ingredients should be breast-fed off.

Side effects

What side effects can the combination of active ingredients of ethinyl estradiol + Desogestrel in Marvelon have? In the following you will learn the most important thing possible, well-known side effects of ethinyl estradiol + Desogestrel in Marvelon. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the drug form of the drug (for example, Tablet, syringe, ointment).

Common: breast tenderness, weight gain, upsets, upset stomach, nausea and vomiting, headaches (also like a migraine).

Uncommon: Depression, changes in libido, facial skin patch (that are enhanced by Sun), pigmentation disorders.

Rare: contact lens problems (poor compatibility), Scheidenentzündungen, fungal infections of the vagina, spotting, liver tumors (benign), high blood pressure, changes of lipid metabolism.

Very rare: Occlusions (blood clots, in liver and intestines), milk, Brustvergößerung, formation of cysts on the ovaries, liver tumors (malignant).

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