Dolomo TN

Application area called by the manufacturer

To this, related with Dolomo TN area there is in-depth information:

  • Pain (mild to moderately strong)

Other components

The following substance not effective components are part of the drug:

  • Dimeticon
  • Hypromellose
  • Corn starch
  • Talcum powder
  • Aluminium oxide (only in night tabs.)
  • Cellulose
  • Dye E 132 (only in night tabs.)
  • Sodium chloride (only in night tabs.)
  • Stearyl oxyethylierter alcohol
  • Silicon dioxide
  • Sorbic acid

So does dolomo TN

Dolomo TN contains the active ingredient combination of acetylsalicylic acid + paracetamol + caffeine + codeine. Below to learn more about the applications and the action of acetylsalicylic acid + paracetamol + caffeine + codeine. Read also the information about the drug group Opioid Painkillers, to which the active substance combination of acetylsalicylic acid + paracetamol + caffeine + codeine belongs. Please note the special effect of dolomo TN is also

Application of the combination of active ingredients: aspirin + paracetamol + caffeine + codeine

The active ingredients are in two different combinations for the pain relief of day (acetylsalicylic acid + paracetamol + caffeine) and to relieve mild to moderately strong pain at night (acetylsalicylic acid + paracetamol + codeine) used.

Following applications of acetylsalicylic acid + paracetamol + caffeine + in-depth information codeine are available:

  • Pain (mild to moderately strong)

Mode of action of acetylsalicylic acid + paracetamol + caffeine + codeine

The active substance combination attacks in different parts of metabolism and soothing effect.

Acetylsalicylic acid is a non-steroidales Antirheumatikum (NSAID). It is soothing, calms, blood verdünnend and anti-inflammatory in higher dosage. The drug inhibits the production of prostaglandins, important chemicals for pain and inflammation in the body tissues. The antipyretic effect of acetylsalicylic acid comes into being through effects on the temperature control centre in the brain. Acetylsalicylic acid also blocks platelet by inhibiting certain enzyme reactions.

Paracetamol is a pain-killing and fever agent, and belongs to the Group of non-opioid pain relievers. It also causes inhibition of prostaglandin production, but primarily in the brain. Paracetamol has little anti-inflammatory properties. In addition, it comes with acetaminophen to inhibit endogenous fever substances in the temperature regulation of the cerebellum. This explains the antipyretic effect.

Caffeine enhances the effects of aspirin and paracetamol and accelerates their effect entry. It is a Xanthine derivative and acts as antagonist to receptors for the amino acid adenosine. This reduces the inhibitory effects of adenosine on the central nervous system (CNS). Caffeine stimulates so heart and circulation, temporarily increases the efficiency and scared away fatigue. It also has a favorable effect on migraine-like headaches because it constricts the blood vessels. The direct effect of caffeine in headache is due to his blood-promoting properties, as well as a reduction of brain pressure.

Codeine is a direct morphine-Abkömmling and one of the active group of opioid pain relievers. It is dose-dependent brain pain-resistant as well as cough stimulus stillend. The mechanism of action of codeine is due to an inhibition of pain management to important posts in the brain and spinal cord. Codeine also influenced the perception of pain in the brain. The active ingredient has also easily soothing properties, on the inhibition of pain which usefully supplements the effect of the combination of the night.

Special features of the effect of dolomo TN

The product contains white day tablets, where are aspirin and acetaminophen with caffeine and blue night tablets in which the two former painkillers combined with codeine.

Application area according to manufacturer’s specifications

  • acute moderate to severe pain

Warnings & precautions

Das Medikament kann auch bei bestimmungsgemäßem Gebrauch das Reaktionsvermögen so weit verändern, dass die Fähigkeit zum Autofahren, zur Bedienung von Maschinen sowie zu sonstigen gefahrvollen Tätigkeiten eingeschränkt ist. Dies gilt insbesondere in den ersten Tagen der Behandlung sowie in Verbindung mit Alkohol.

Bei Auftreten von schwarzem Stuhl (Teerstuhl) wöhrend der Einnahme ist sofort der Arzt zu benachrichtigen.

Wenn während der Einnahme des Medikaments Zeichen einer Infektion wie Rötung, Schwellung, Überwärmung, Schmerz und Fieber neu auftreten oder sich verschlimmern, sollte unverzüglich der Arzt zu Rate gezogen werden.

An anemia by hidden stomach intestine lost can occur after prolonged use of the drug. Regular medical blood count checks are advisable.

The drug must be removed immediately at the first signs of a hypersensitivity reaction.

The doctor or dentist about use of the drug must be informed prior to operations.

Dizziness or hearing sounds arise with use of the drug, a doctor is immediately to notify, as it can be signs of poisoning.

Medicines can cause allergic reactions. Evidence for this can be: redness, runny nose, itching, swelling of the mucous membrane, itching and redness of the eyes, narrowing of the Airways (asthma). In rare cases, there may be allergic shock with loss of consciousness.

Should you perceive signs of an allergic reaction, immediately inform a doctor.


What interactions of the combination of active ingredients of acetylsalicylic acid + paracetamol + caffeine + codeine in dolomo TN are known? It is important to note that the interactions can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

Interactions with the combo component of aspirin: aspirin enhances the effect of anticoagulants (blood coagulation retardant means) such as coumarin derivatives or heparin, which can lead to severe bleeding. The combination with Clopidogrel and vitamin K antagonist (warfarin, Dicoumarol) is particularly dangerous. Concurrent use of glucocorticoids or alcohol consumption increases the risk of stomach bleeding. Even with concurrent use of valproic acid (disambiguation), the bleeding tendency is increasing.

Acetylsalicylic acid strengthened effect and side effects of Herzmittels digoxin, lithium and barbiturates (pills) such as, for example, Chloramphenicol antibiotics such as sulfonamides and trimethoprim, oral antidiabetic drugs, triiodothyronine (combat thyroid disease), theophylline (combat asthma), methotrexate (combat rheumatism and cancer), as well as other non-steroidal anti-inflammatory drugs with concurrent administration.

Acetylsalicylic acid reduce the effects of high drainage resources (loop diuretic), funds against high blood pressure (antihypertensives) and Urikosurika (means against gout) simultaneous use.

Acid-binding means (antacids) speed up the Elimination of acetylsalicylic acid and thereby reduce its effect.

Interactions with the paracetamol combination element: the repeated ingestion of paracetamol over more than a week enhances the effect of anticoagulants such as warfarin and Cumarinen. It is therefore necessary to a thorough medical examination of blood clotting.

Liver damage can occur while taking acetaminophen and pills, AEDs such as phenobarbital, phenytoin or carbamazepine, the antibiotic Rifampizin and alcohol abuse.

Medium such as Propanthelin which slow gastric emptying, the absorption of paracetamol in the body and thus can delay entry into the action in the inhibition of pain.

Wenn gleichzeitig die Magenentleerung beschleunigende Wirkstoffe ( Prokinetika ) wie Metoclopramid eingenommen werden, tritt die Wirkung von Paracetamol schneller ein.

Bei gleichzeitiger Anwendung von Paracetamol und dem Viren-Hemmer Zidovudin treten vermehrt Mangelzustände weißer Blutkörperchen (Neutropenien) auf.

Wechselwirkungen mit dem Kombinationsbestandteil Coffein: Coffein wirkt den beruhigenden Effekten zahlreicher Wirkstoffe wie Schlafmitteln , Betablockern und Mitteln gegen Allergien entgegen.

Coffein verstärkt die herzbeschleunigende Wirkung der Sympathomimetika und des Schilddrüsenhormons Thyroxin . Dies kann zu Unruhezuständen und Herzjagen führen.

Bei einigen Wirkstoffen wie den Benzodiazepinen können die Wechselwirkungen mit Coffein unterschiedlich und nicht voraussehbar sein.

Oral contraceptives (pill), the Säureblocker cimetidine (H 1 – antihistamine) and the Alkoholentwöhnungsmittel of disulfiram decrease the caffeine removal in the liver, accelerate him sleeping like the barbiturates and nicotine. So, it modifies the duration of action of caffeine.

The Elimination of asthma-Mittels theophylline is reduced by caffeine and its effects so increased.

Caffeine increases the dependency potential of ephedrine.

Interactions with the part of the combination codeine: when simultaneous use of codeine induces and pills, drugs, other Central absorbing funds, funds for the treatment of allergies (antihistamines), hypotensive means or alcohol consumption to increased fatigue and dizziness occur. In addition, the codein-related impairment of breathing can be strengthened here.

This respiratory impairment also occurs with concurrent administration of tricyclic antidepressants or Opipramol.

To a strengthening of the central nervous system effects and other side effects not predictable extent can occur while taking MAO inhibitors. Therefore, code content-drugs only two weeks may be applied after the end of treatment with MAO inhibitors.

The effect of pain medication is reinforced by codeine. Simultaneous use of certain opioider pain reliever (partial Opioidagonisten/-antagonisten), the effect can be mitigated by codeine.

Gastric acid resistant active ingredients such as cimetidine, affecting the liver metabolism, can amplify the effects of codeine.


The medicinal product is approved only for adults and adolescents over 14 years!

For the day, taking one or two white tablets daily as a single dose. If necessary, a repeat is daily possible up to a total of six white tablets.

For the night 20 to 30 minutes before bedtime be daily as a single dose one to two of blue night tablets ingested, but per night no more than three blue tablets. For aggregation of day and night form the maximum dose is 6 tablets in 24 hours.

The tablets should be taken with plenty of liquid.


The following information on contra-indications in the application of Dolomo TN in General, pregnancy & breast-feeding and children. It is important to note that the contra-indications can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

When dolomo TN cannot use?

The combination may not be applied:

  • When hypersensitivity to salicylates, acetylsalicylic acid, paracetamol (acetaminophen) or other non-steroidal anti-inflammatory drugs, caffeine or codeine
  • with gastric or duodenal ulcers, as well as increased bleeding (hemorrhagic Diathesis)
  • in acute asthma – seizures, disorders of Atemzentrums and the respiratory function
  • in dependence on Opioid Painkillers
  • impairment of consciousness, coma or diseases with increased intracranial hypertension
  • low blood pressure due to lack of fluid (hypovolemic)
  • in the last third of pregnancy and in children and adolescents under the age of twelve.

The combination may be used only after careful risk benefit by a doctor when:

  • Hypersensitivity reactions against analgesics (analgesics intolerance) in the form of asthma bronchial asthma, hay fever, nasal, chronic respiratory infections and hypersensitivity to pain and Rheumamittel of all kinds
  • allergic skin reactions (allergic Diathesis) such as itching or hives
  • severe hepatic impairment by chronic alcohol abuse or liver
  • increased values of yellow seal (Gilbert Gilbert’s disease)
  • Heart muscle weakness (heart failure)
  • Kidney failure and dialysis patients
  • chronic and recurrent gastric and duodenal disorders
  • hereditary deficiency of the enzyme glucose-6-phosphate dehydrogenase. Here is a risk of anaemia by the resolution of the red blood cells.


  • Anxiety disorders (anxiety syndrome)
  • concurrent treatment with coagulation inhibitory drugs (anticoagulants) such as coumarin derivatives or heparin (with the exception of a low-dose heparin therapy)
  • simultaneous use of valproic acid and acetylsalicylic acid, especially in infants and young children.

Opioid analgesics cause constipation, the combination may be taken because of its codeine content when constipation not over a longer period.

What must you consider when pregnancy and breast-feeding?

Taking the combination during pregnancy is not recommended. All active substances pass through the placenta and appears in the body of the unborn.

Acetylsalicylic acid has led animal in high doses to abnormalities in the first third of the pregnancy. In the first two thirds of the pregnancy the drug should be taken only after consultation with a doctor. In the last third of pregnancy, acetylsalicylic acid may be used under no circumstances as the child can take serious damage. There may also be a delay and extension of the birth by the labor-inhibiting effect of acetylsalicylic acid.

No adverse effects on the child are known for acetaminophen. However, should paracetamol be used during pregnancy only after physician’s order.

In the first four months of pregnancy, malformations of the respiratory system have been increasingly identified during treatment with codeine. Codeine is captured in the last three months of pregnancy, withdrawal symptoms are so in the newborn. At birth, respiratory distress and shortness of breath can occur in the newborn by the resulted treatment.

No increased risk in the course of the pregnancy and child development are known for caffeine at usual therapeutic doses, or coffee.

Acetylsalicylic acid, paracetamol and caffeine go over into breast milk. During the Silliman the State and behavior of the infant can be affected by aspirin and caffeine as the body of the infant can not build the active ingredients. Adverse consequences for the baby have so far not known.

Codein geht in großem Umfang in die Muttermilch über, sodass Säuglinge Codeinvergiftungen im schlimmsten Falle mit Atemstillstand erleiden können, wenn die Mutter Codein in hohen Dosen einnimmt. Falls eine Verordnung während der Stillzeit notwendig wird, sollte das Stillen für die Dauer der Therapie unterbrochen werden.

What is taken into account in children?

Die Gabe der Wirkstoffkombination an Säuglinge und Kleinkinder ist verboten.

In children and adolescents with suspected cancers or chickenpox the combination must be used with a doctor and then only when other measures are not applied, only after consultation. Should occur after taking to long-lasting vomiting, so this can be a symptom of Reye’s syndrome, which requires immediate medical treatment.

Side effects

What side effects can the combination of active ingredients of acetylsalicylic acid + paracetamol + caffeine + have codeine in dolomo TN? In the following you will learn the most important thing possible, well-known side effects of aspirin + paracetamol + caffeine + codeine in dolomo TN. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the drug form of the drug (for example, Tablet, syringe, ointment).

Very common side effects: gastrointestinal problems such as stomach pain, micro-bleeding, constipation, fatigue.

Common side effects: insomnia, restlessness, Herzjagen, shortness of breath, diarrhea, hypersensitivity reactions such as bouts of shortness of breath, skin reactions (especially for asthmatics), mild headache, slight drowsiness.

Uncommon side effects: stomach bleeding, stomach ulcers, hypersensitivity reactions such as redness, itching, urticaria, dry mouth, insomnia, ringing in the ears.

Rare side effects: liver dysfunction, renal impairment, lack of blood sugar, reduce the uric acid excretion, with risk of gout – seizure, allergic rash.

Very rare side effects: changes of Blutbilds in the sense of an allergic conditional lack of blood platelets (thrombocytes) or on white blood cells (leukocytes), euphoria, dependency (in higher doses), blood pressure, cardiac arrhythmia, movement uncertainties, visual disturbances, Sehleistung degradation, poor interaction between vision and moving, breathing resistance, muscle spasms, internal organs, loss of consciousness, blood pressure, respiratory distress, shortness of breath, pulmonary dysfunction with water retention in the lungs, bronchial cramps, hypersensitivity reactions such as Quincke’s oedema, shortness of breath, sweating, blood pressure until the shock, Blood count changes such as agranulocytosis and Pancytopenia, severe allergic skin reactions, including Stevens-Johnson Syndrome and erythema multiforme.

Occasionally occurring side effects: deterioration of infection-induced inflammation, Bindegewebsentzündungen, weight gain.

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