All fields of application by the manufacturer
Field of application to this, with nifedipine STADA 5 mg in conjunction the there is more in-depth information:
- Angina pectoris
Other components
Substance not effective parts are included in the drug:
- Eisen(II,III)-OXID (E 172)
- Eisen(III)-OXID (E 172)
- Titanium dioxide (E 171)
- Eisen(III)-hydroxid-OXID H2O (E 172)
- Gelatine
- purified water
- Glycerol 85 vol.%
- MACROGOL 400
- Saccharin sodium 2H2O
So is nifedipine STADA 5 mg
Nifedipine STADA 5 mg contains the active ingredient of nifedipine. Below you find out more about the fields of application and the action of nifedipine. See also the information about the drug group of agents to which the active ingredient of nifedipine belongs. Note is also the special effect of nifedipine STADA 5 mg
- Areas of application of the active substance: nifedipine
- Nifedipine is used in the treatment of high blood pressure, which has no organic causes (essential hypertension).
In addition, nifedipine is used for an inadequate oxygen supply to the heart muscle (coronary artery disease). It regulates the active ingredient appropriate vascular heart stress (load angina, chronic stable angina pectoris) and treated cramping States with insufficient oxygen supply to the heart muscle (Vasospastische Prinzmetal Angina, angina pectoris, variant angina).
Arterial Circulatory disturbances in the fingers (Raynaud’s disease) or the treatment of blood pressure-related emergency patients (Hypertensiver emergency) are a further area of application of nifedipine.
Following applications of nifedipine, detailed information is available:
- High blood pressure
- Angina pectoris
- Arterial Circulatory Disorders
- Effect of nifedipine
Nifedipine is an agents and the key ingredient of the subgroup of Dihydropyridine.
It blocks the channels in the wall of the Gefäßmuskulatur and prevents so that calcium into the muscle cells flowing in. The muscle cells relax and expand the blood vessels. This improves blood flow and blood pressure drops.
Nifedipine dilates the blood vessels that supply the heart with oxygen and thus facilitates the work of the heart. Narrow or cramped blood vessels to the heart can also be the cause of heartache. In certain forms of heart tightness (angina pectoris), nifedipine also causes an improvement of complaints.
Nifedipine is well received by the body of the gastro intestinal tract and is present in sufficient concentration in the blood so quickly. If the active substance but is metabolised in the liver passage to a high extent on the liver, the coming into effect share of nifedipine in the body is greatly humiliated. After two to four hours is only half of the original amount of drug in the blood. Therefore, nifedipine is included in many medicines in the form of delay. Retardmittel set free the active ingredient is delayed, but over a longer period. Thus, an approximately constant and sufficient concentration in the blood is ensured.
Special features of the effect of nifedipine STADA 5 mg
Nifedipine STADA 5 mg is suitable due to the low amount of drug for patients with severe circulatory disorders of the brain and for patients who expect an excessive reaction to the Nifedipingabe due to their low body weight or multiple treatment with antihypertensive means.
Also patients who respond with side effects more sensitive to Nifedipn should be set individually 5 mg with nifedipine STADA.
Warnings & precautions
- So far the drug can affect the responsiveness that driving and using machines are dangerous. This is true especially in conjunction with alcohol.
- In impaired liver function the drug can lead to a greater reduction in blood pressure.
- Severe circulatory disorders of the brain (cerebrovaskuläre disease) are available, the doctor must choose a lower dosage of the drug.
- The drug should be taken with grapefruit juice.
- In the event of cardiac arrhythmia or aggravation of a heart muscle weakness, the treatment is to cancel.
- A slow dose reduction should be done to end the treatment with the drug.
- The discontinuation of the drug should be done gradually.
- Medicines can cause allergic reactions. Evidence for this can be: redness, runny nose, itching, swelling of the mucous membrane, itching and redness of the eyes, narrowing of the Airways (asthma). In rare cases, there may be allergic shock with loss of consciousness.
Should you take signs of an allergic reaction, immediately inform a doctor.
Interactions
The interactions of the active substance nifedipine in nifedipine STADA 5 mg are known? Please note that the interactions can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).
A stronger antihypertensive effect occurs (diuretics) and gastric acid resistant products such as cimetidine or ranitidine with concurrent administration of other antihypertensive means (drugs), beta-blockers, nitrates, tricyclic antidepressants, drainage products.
Nitrates also increase the blood pressure lowering effect of nifedipine and can accelerate also en heartbeat.
When combined with the blood pressure lowering diltiazem, nifedipine mining is delayed in the body and can cause undesirable side effects. A close monitoring and dosage adjustment by the physician is needed here.
Beta blockers such as propranolol also lead to a greater reduction in blood pressure, sometimes even to the training of a heart muscle weakness (heart failure). Here, a careful medical supervision is required.
Concurrent administration of Herzmittels digoxin, theophylline (for asthma) or cyclosporin (against organ immunosuppression) or antibiotics from the Group of the cephalosporins (such as for example Cefixim) increase the blood levels of those substances in the blood and thus their harmful side effects.
Antiarrhythmics like Amiodarone and quinidine reduce the force of heart beat and are reinforced in their injurious effects by nifedipine.
Gastric acid-resistant agents (Antiazida) such as cimetidine or ranitidine amplify the effect of nifedipine and can lead to high blood pressure.
Rifampicin promotes the reduction of nifedipine in the body, which weakens the effect.
In a cancer treatment vincristine with nifedipine used, the excretion is reduced by vincristine, which may increase the side effects of vincristine. A dose reduction of vincristine may be required.
The duration of therapy with antiepileptic phenytoin and carbamazepine decreases the effect of nifedipine.
Simultaneous use of opioid analgesic fentanyl or other sleeping and drugs a low blood pressure occurs occasionally.
For the treatment of fungal infections itraconazole used, the effect is possibly reinforced by nifedipine.
Nifedipine should be taken with grapefruit juice. Grapefruit juice prevents the degradation of nifedipine in the body and strengthens the blood pressure lowering effect.
