The active ingredient is used to the so-called active immunization against yellow fever. This protection need persons who travel to areas with occurrence of yellow fever, they pass through or live there or travel to countries that require an international vaccination certificate (possibly regardless of which countries have been visited previously) for entry into the country.
Is this ingredient for what purposes?
Immune cells form against yellow fever virus
Form antibodies against yellow fever virus
trigger a mild yellow fever infection
Price comparison
The table below shows all collected medication containing the active ingredient of yellow fever live vaccine:
| Drug | Price per 10 E of the active substance | Dosage of the active substance | Packungs-size and dosage form | Cheapest price per Pack (with surcharge),(Versandkosten) |
| Stamaril | 0.31 EUR | 1000 E per milliliter pre-filled syringe | 10 Ml syringes | Price 308,96 EUR (10,00 EUR), (0,00 EUR shipping) price comparison |
| Stamaril | 0.40 EUR | 1000 E per milliliter pre-filled syringe | 1 ML prefilled syringe | Price 39,57 EUR (5.00 EUR), (3.98 EUR shipping) price comparison |
So does yellow fever live vaccine
Learn more on the applications and the action of yellow fever live vaccine below. Read also the information about the vaccines, which is the active ingredient of yellow fever live vaccine drug group.
Fields of application of the active substance: yellow fever live vaccine
The active ingredient is used to the so-called active immunization against yellow fever. This protection need persons who travel to areas with occurrence of yellow fever, they pass through or live there or travel to countries that require an international vaccination certificate (possibly regardless of which countries have been visited previously) for entry into the country.
But also those who work with potentially infective material (for example, laboratory staff) need such vaccination.
To comply with applicable requirements and the official recognition yellow fever vaccines from a yellow fever vaccination authority recognised by the World Health Organization (WHO) have administered and the vaccination must be entered in an international vaccination certificate. The vaccination certificate is from the tenth day after the vaccination for ten years valid and after a re-vaccination immediately.
Mode of action of yellow fever live vaccine
Yellow fever live vaccine is one of the active group of vaccines. The active ingredient contains live but weakened viruses of yellow fever. As in other Lebendimpfstoffen with such attenuated viruses, healthy vaccinated persons develop a mild infection. During its course, their body’s defenses makes targeted certain immune cells (B and T cells), as well as antibodies to the virus.
The protection begins about ten days after administration of the vaccine. Even though international health regulations to maintain a valid vaccination certificate request a re-vaccination every 10 years, yet a certain protection is probably even after expiry of this period.
Warnings and precautions
The drug is not suited to the vaccination of children that are younger than six months.
The vaccine may get into the bloodstream and should preferably under the skin or injected into the muscle.
Remedy ingredients sometimes trigger allergic reactions. Should you perceive signs of an allergic reaction, so you tell your doctor or pharmacist promptly.
What interactions shows yellow fever live vaccine?
It is important to note that the interactions can be different depending on the pharmaceutical form of a drug (for example, Tablet, syringe, ointment).
Should the vaccine at the same time with one or more injectable vaccines be given, so each vaccine on a different site should be applied (preferably the other arm or the other buttock).
At the same time, the vaccine can be administered with measles vaccine if this corresponds to the official recommendations. The same applies to the common application with vaccines against typhoid or inactivated hepatitis A virus.
Because the vaccination reaction can be used to the disease, the vaccine not to persons must be given, be treated with immunosuppressive drugs (such as with cytotoxic drugs, glucocorticoids to taking or such to apply on the skin or inhalation, when higher than normal doses).
Contra-indications
The following information about contra-indications in the application of yellow fever live vaccine in General, pregnancy & lactation, and in children. It is important to note that the contra-indications can be different depending on the pharmaceutical form of a drug (for example, Tablet, syringe, ointment).
When yellow fever live vaccine cannot use?
The vaccine should not be administered in
- Hypersensitivity reactions to eggs and chicken protein because the vaccine is obtained from these
- serious hypersensitivity reactions after a previous dose of a yellow fever vaccine
- Weakness of the body’s own defense, is they inherited, acquired by disease or by drugs caused as, for example, by glucocorticoids (for taking and high-dose forms thereof to apply on the skin or inhaling), by treatment with cytostatic or radiation
- Dysfunction of the thymus gland in prehistoric times (ulcers of thymus or removal of the thymus)
- HIV infection with certain complaints (AIDS)
- HIV infection without complaints, but with proven reduced immune function
- acute severe febrile diseases.
Special medical care is for persons over 60 years. They seem to have a particular risk of nerve damage by the vaccination. The signs may be: fever, malaise, muscle pain, headache and blood pressure. End of the next clinical syndromes can it evolve: acidification of the body (metabolic acidosis) resolution of muscle and liver tissue, changes of doctors, kidney failure and respiratory arrest. Therefore the vaccine should be administered only to persons, for which a considerable risk of yellow fever. Vaccination can cause severe bruising in persons with impaired blood clotting when in the muscle. Therefore, she should be given to haemophiliacs, lack of platelets or concurrent treatment with anticoagulants exclusively under the skin.
What must you consider when pregnancy and breast-feeding?
No animal experiments on the impact in pregnancy were carried out. Therefore, the potential risk for humans is unknown, and the vaccine should be administered by pregnant women only when the unique need, and only after careful medical risk benefit.
There is a possible risk of transmission of vaccine virus tribe of breastfeeding mothers to babies. Therefore, the vaccine only if absolutely necessary may be, for example, to prevent a yellow fever outbreak and after careful PrimePortal by the physician.
What is taken into account in children?
The vaccine should be given to children in General not before reaching the ninth month. Vaccination of children from the completed sixth month of life is prohibited. This also applies to children HIV of Kroft mothers. The children are themselves infected with HIV and if they have completed at least the sixth month of life, they should be examined in the need of protection against yellow fever to the clarification of the immunization ability of specialist paediatricians.
Children between the completed sixth and the completed ninth month of life should be vaccinated only in special circumstances (for example, during a large outbreak of yellow fever), and according to the valid official recommendations.
What side effects can yellow fever live vaccine have?
Below, you will learn the most important thing possible, well-known side effects of yellow fever live vaccine. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the pharmaceutical form of a drug (for example, Tablet, syringe, ointment).
- Very common side effects: headache, reaction to the Impfort (including pain, redness, bruising, induration, swelling).
- Common side effects: nausea and vomiting, diarrhea, muscle aches.
- Uncommon side effects: abdominal pain, joint pain.
Side effects of unknown frequency: Lymphdrüsenschwellung, allergic shock, facial swelling (angioedema), diseases of the nervous system (indicated by high fever with headache;) Consequences are: confusion, lack of drive, encephalitis, brain dysfunction, strokes, seizures, Guillain-Barre syndrome, failure of nerve groups, rash, hives, multiple organ dysfunction syndrome with fever, fatigue, muscle pains, headache, or drop in blood pressure; Consequences are: body acidification (metabolic acidosis), resolution of muscle and liver cells, lack of lymphocytes and platelets, renal failure and respiratory arrest.
Specialties: A congenital or acquired immune deficiency can be a risk factor for nerve disease following vaccination, a thymus disease history favors a multiple organ failure. An age over 60 years can promote both complications.
