Ethinyl estradiol + Norgestimat

Is this combination of active ingredients for what purpose?

  • Prevent pregnancy

So does ethinyl estradiol + Norgestimat

Learn more about the applications and the action of ethinyl estradiol + Norgestimat below. Read also the information about the active group of estrogen-progestin combinations to prevent, to which the active substance combination ethinyl estradiol + Norgestimat belongs.

Application of the combination of active ingredients: ethinyl estradiol + Norgestimat

The combination of active ingredients of ethinyl estradiol and Norgestimat is used for the hormonal contraception (“pill”, “Birth control pill”).

Following applications of ethinyl estradiol + Norgestimat more detailed information are available:

  • Contraception

Effect of ethinyl estradiol + Norgestimat

Ethinyl estradiol and Norgestimat belong to the Group of estrogen progestin combinations to prevent.

Ethinyl estradiol is related to the body’s own hormone estradiol from the Group of estrogens. Norgestimat is a progestin (Gelbkörperhormon) and is similar to progesterone.

The combination of estrogen and progestin supported the preparation of the body on a pregnancy, ovulation and the period of regression in the menstrual cycle of a woman. This is done by these hormones are awarded varies on certain days of the cycle.

By using the combination of the active ingredients, increased amounts of oestrogen and progestin are offered the body. So a pregnancy is faked the body. As a result, ovulation is inhibited and the thickening of the Gebämutterschleimhaut that is necessary for an implantation of the egg, absence. This means a double protection against pregnancy. Norgestimat in addition thickened the mucus at the entrance of the uterus so that sperm can get worse.

Warnings and precautions

Does the combination not protect against HIV infection or other sexually transmitted diseases.

Laboratory values of liver, kidney and thyroid gland can be changed by the application of the combination of the active ingredients.

Remedy ingredients sometimes trigger allergic reactions. Should you perceive signs of an allergic reaction, so you tell your doctor or pharmacist promptly.

What interactions show ethinyl estradiol + Norgestimat?

It is important to note that the interactions can be different depending on the pharmaceutical form of a drug (for example, Tablet, syringe, ointment).

The contraceptive action of the combination ethinyl estradiol and Norgestimat can be weakened by the concomitant use of certain active substances or lifted. These include:

  • Sleep aid from the Group of barbiturates
  • the antibiotic rifampicin, griseofulvin, ampicillin and tetracycline
  • virus-resistant funds such as ritonavir and nelfinavir
  • St. John’s wort
  • Antiepileptics like Barbexaclone, Hydantoin, carbamazepine, phenytoin, Primidone, Oxcarbazepine, topiramate and Felbamate
  • the Gichtmittel Phenylbutazone
  • Activated carbon

The virus-resistant means indinavir can reinforce the effect of the combination. Since ethinyl estradiol and Norgestimat affect blood sugar, insulin and oral antidiabetic drugs may in their dose must be adjusted. Laboratory values of liver, kidney and thyroid gland can be changed by the application of the combination of the active ingredients.


The following gives details of contra-indications for the purposes of ethinyl estradiol + Norgestimat in General, pregnancy & lactation, and children. It is important to note that the contra-indications can be different depending on the pharmaceutical form of a drug (for example, Tablet, syringe, ointment).

When may ethinyl estradiol + Norgestimat not be used?

Ethinyl estradiol and Norgestimat may not be applied when:

  • Hypersensitivity against one of the active ingredients of the combination
  • Pregnancy
  • existing or former malignant tumors that would grow further by administration of ethinyl estradiol (such as breast cancer)
  • Herpes infections in a previous pregnancy (herpes gestationis)
  • untreated growths of the uterine lining
  • diagnostic in clarified bleeding from the vagina
  • acute or previous severe liver disorders (such as liver tumors, liver, jaundice, bile congestion, Dubin-Johnson Syndrome, rotor syndrome), as long as that certain liver (transaminases) not have normalized
  • acute or previous blood vessel diseases, which led to occlusions (thrombosis) of arteries or veins, such as about serious diseases, vein thrombosis, phlebitis (thrombophlebitis), disorders of blood clotting, pulmonary embolism, stroke, angina pectoris, myocardial infarction, and valvular heart disease
  • hard behandelbarem high blood pressure
  • Sickle cell anemia
  • severe lipid metabolism disorders or obesity
  • Middle ear hearing loss has made worse during previous pregnancies
  • Migraine.

The following diseases the combination of active substances can be applied while, the doctor must however, check that the development of the treatment through ongoing control of the corresponding laboratory values and, if necessary, cancel the treatment:

  • Breast cancer in the family (kinship first degree)
  • previously encountered disorders
  • a pronounced tendency toward varicose veins
  • Rise in blood pressure
  • Diabetes (diabetes mellitus)
  • Lupus Erythematosus
  • Depression
  • previous lighter liver and gallbladder diseases
  • Epilepsy
  • Asthma
  • Chorea minor (Chorea)
  • multiple sclerosis
  • Endometriosis and benign uterine tumors
  • Degradation of blood calcium levels
  • lighter lipid metabolism disorders or significant overweight
  • Diseases of breast (Mastopathy)
  • Use of contact lenses

Taking the combination of active ingredients promotes the emergence of occlusions (thrombosis), which can lead to dangerous cardiovascular disease. This risk can by additional risk factors such as smoking, high blood pressure, blood clotting or disorders of lipid metabolism as well as previous occlusions and a longer restraining further be increased (for example through confinement). After an inflammation of the liver, treatment should be initiated with ethinyl estradiol and Norgestimat not before six months.

What must you consider when pregnancy and breast-feeding?

The scope of ethinyl estradiol and Norgestimat excludes a treatment with the combination of the drug during pregnancy.

The production of breast milk can be reduced by ethinyl estradiol and Norgestimat. Also, small amounts of active ingredient in breast milk and hence in the infant can go over. To avoid damage to the child before an application of the combination of active ingredients should be breast-fed off.

What is taken into account in children?

The scope of ethinyl estradiol and Norgestimat excludes a treatment of children with the combination of the active ingredients.

What side effects can ethinyl estradiol + Norgestimat have?

Below, you will learn the most important thing possible, well-known side effects of ethinyl estradiol + Norgestimat. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the pharmaceutical form of a drug (for example, Tablet, syringe, ointment).

Very frequent: Durchbruch-and spotting, headache (rare migraine).

Common: water retention (oedema), nausea and vomiting, abdominal pain, changes in weight, mood swings, depression, nervousness, dizziness, changes in libido, acne, breast pain, breast sensitivity, breast enlargement, fluid secretion of glands, rule menstrual pain (dysmenorrhea), Scheidenentzündung, vaginal discharge, fungal infections.

Uncommon: rise in blood pressure, stomach cramps, flatulence, changes of appetite, changes of blood lipids, rash, spots on the face (possibly permanently), pigmentation disorders, body behaarung growth (HIRSUTISM), hair loss.

Rare: Changes of blood glucose values, nodes (education painful nodes in the skin), contact lens problems (poor compatibility).

Very rare: Varicose veins, gallbladder disease, gallstones, pancreatitis, liver cancer, worsening disruption of breakdown of hemoglobin (Porphyria), rash with node formation (wide), Sehnerventzündung.

More side effects (no frequency specified): pre-menstruelles syndrome, herpes gestationis, changes of cornea, changes in blood sugar levels, renal impairment, intestinal inflammation, growth of benign uterine tumors.

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